In Point Coupee Parish an 18-wheeler carrying sugar cane and a train collided, causing the train to jump the tracks.
According to state police, the 18-wheeler is responsible for the accident. Officials say it pulled out in front of the train.
Damage to the track is extensive and is expected to take several days to fix. Traffic will be rerouted around LA 415 until the area has been cleaned of debris.
The driver of the truck received minor injuries.
Troopers urge everyone to use caution when crossing railroad tracks.